Croscarmellose sodium is a cross linked polymer of carboxy methyl cellulose sodium and used in pharmaceutical formulation as a disintegrant. Croscarmellose sodium occurs as an odorless, white or grayish white powder.

Disintegrants facilitate the breakup of a tablet in the intestinal tract after oral administration. Cross-linking allows enhanced bioavailability of the drug through superior drug dissolution. Without a disintegrant, tablets may not dissolve appropriately and may affect the amount of active ingredient absorbed, thereby decreasing effectiveness.

ADVANTAGES
  • Fast disintegration & dissolution
  • Better stability
  • Good Flowability and mixing properties
  • Facilitate breakup of tablets
APPLICATIONS
  • It is used in oral pharmaceutical formulations as a disintegrant for capsules, tablets and Granules
  • It is used in both direct-compression and wet-granulation processes
UNIQUE FEATURES of SANCEL
  • Greater level of dissolution of tablets
  • Excellent API stability
  • Cost-effectiveness
  • GMO Free
Product Specification
Compendial Standards USP – NF BP
Description Fine to coarse, White or off White, free flowing Powder, Odourless or almost odourless White or greyish white powder
Identification A, B,C Complies Complies
pH 5.0 – 7.0 5.0 – 7.0
Loss on Drying % NMT 10 NMT 10
Sodium Chloride and Sodium Glycolate, Sum % NMT 0.5 NMT 0.5
Heavy Metals, PPM NMT 10 NMT 20
Degree of Substitution 0.60 to 0.85 0.60 to 0.85
Water Soluble Material % NMT 10.0 NMT 10.0
Settling Volume, ml 10 to 30 10 to 30
Residue on Ignition, % 14 to 28 14 to 28
Microbiology Limits:
Total Aerobic Microbial Count, cfu/g NMT 1000 NMT 1000
Total Yeast And Mold Count, cfu/g NMT 100 NMT 100
Escherichia Coli Absent in 1g Sample Absent in 1g Sample
Salmonella Species Absent in a 10g Sample Absent in a 10g Sample
Pseudomonas Aeruginosa Absent in 1g Sample Absent in 1g Sample
Staphylococcus Aureus Absent in 1g Sample Absent in 1g Sample
Packaging Details

Available Packaging Type

Type Size
HDPE Bags 25 Kg
HDPE Bags 20 Kg
Paper Bags 25 Kg
Paper Bags 20 Kg
FIBC 300 Kg

*Our standard packaging is in 25 kg Bags. We can also customize packaging as per customers request at additional cost.

Container Palletized Non-Palletized
20 Ft. (Approx Wt.) 10,000 Kg 12,000 Kg
40 Ft. (Approx Wt.) 20,000 Kg 24,000 Kg

Technical Product Data Sheets & Samples are available on request

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