SANCEL® MCC with Sodium Carboxymethylcellulose — Co-Processed Excipient for Faster Disintegration and Stronger Compacts

Formulators demanding faster tablet disintegration without compromising compaction strength now have a single-ingredient solution. SANCEL® MCC with Sodium Carboxymethylcellulose is a sophisticated co-processed excipient that merges the binding power of MCC with the superior disintegrant action of sodium CMC. The result is a multifunctional excipient that simplifies your formulation, reduces your bill of materials, and delivers clinically superior disintegration profiles.

What Is SANCEL® MCC with Sodium Carboxy Methyl Cellulose?

This product is a co-processed combination of Microcrystalline Cellulose (MCC) and Sodium Carboxymethylcellulose (Sodium CMC), produced through a controlled co-processing technique that ensures intimate, uniform interaction between the two components. Sodium CMC, a water-swellable polymer, is incorporated within the MCC matrix, enabling rapid wetting and swelling upon contact with gastrointestinal fluids. This delivers a burst disintegration effect superior to MCC alone, while the MCC base maintains the compact’s mechanical strength.

Key Benefits & Why Formulators Choose NBE SANCEL® MCC with Sodium Carboxy Methyl Cellulose

Dual Functionality:

Combines binder and disintegrant functions in a single excipient — reducing formulation complexity and cost.

Rapid Disintegration:

Sodium CMC’s hydrophilic nature draws moisture into the tablet core rapidly, accelerating disintegration far beyond standard MCC.

Maintained Compactibility:

Despite the hydrophilic CMC component, the product retains excellent compactibility — producing robust tablets.

Simplified Bill of Materials:

Replace two or more excipients with one co-processed ingredient — streamlining procurement and QC testing.

Improved Bioavailability:

Faster disintegration translates to faster API dissolution, potentially improving bioavailability for BCS Class I and III drugs.

Packaging Details – Available Packaging Type

Type	Size
HDPE Bags	25 Kg
HDPE Bags	20 Kg
Paper Bags	25 Kg
Paper Bags	20 Kg
FIBC	400 Kg

*Our standard packaging is in 25 kg Bags. We can also customize packaging as per customers request at additional cost.

Container Capacity

Container	Palletized	Non-Palletized
20 Ft. (Approx Wt.)	10,000 Kg	12,000 Kg
40 Ft. (Approx Wt.)	20,000 Kg	24,000 Kg

Why Source SANCEL® MCC with Sodium Carboxy Methyl Cellulose from NB Entrepreneurs?

With nearly five decades of manufacturing experience since 1976, cGMP-certified production facilities, and a track record serving 1,000+ customers across 192 cities and 20+ countries — including 75+ USFDA-accredited facilities — NB Entrepreneurs delivers SANCEL® MCC with Sodium Carboxy Methyl Cellulose that meets the strictest pharmacopoeial standards. Our 18,000 MT/year MCC capacity ensures reliable bulk supply with 99.4% perfect order rate. Every batch ships with a full Certificate of Analysis, MSDS, and technical data sheet. Our dedicated technical team supports grade selection, formulation compatibility, and regulatory documentation — making us far more than just a supplier.

Frequently Asked Questions

What is the difference between co-processed excipients and physical blends?

Co-processed excipients are manufactured by combining components at a fundamental level during production, creating intimate contact between molecules. A physical blend simply mixes finished particles together. Co-processed excipients deliver more consistent, reproducible performance and often outperform equivalent physical blends significantly.

Does sodium CMC affect tablet hardness?

In SANCEL® MCC-CMC, the MCC component ensures robust tablet hardness is maintained. The sodium CMC does not compromise mechanical strength at typical usage levels; it primarily affects disintegration behaviour upon contact with aqueous media.

MCC with Sodium CMC