All medications are comprised of two elements the API and excipient. API is the active ingredient which is the drug and the excipients are the substances that convey the drug to the recipient. Excipients are synthetically inert substances.
Pharmaceutical Excipients are pivotal to the medical industry. An excipient has no therapeutic properties. The standard reason for its existence is to streamline the manufacturing of the medication item and at last encourage physiological ingestion of the medication. Characteristics of excipient play a key role in effecting blending and final product quality.
Selecting excipients for tablet manufacturing is a vital process. A precisely picked excipient may lessen manufacturing costs by being multifunctional or may improve user’s experience by offering taste veiling properties. An excipient should best suit the planned dose type, the particle size of API show awesome flow properties, high density, absorb high moisture and highly hygroscopic.
Blend homogeneity can be examined on content uniformity analysis of the API. Getting proper concentration of excipient concentration at appropriate particle size which enhances the flow of API improves tablet manufacturing and has an impact on uniformity of content which helps in attaining the uniformity of blend.
Reference:
https://www.pharma-excipients.ch/basics/excipient-selection-considerations/