Co-Processed MCC

MCC with Lactose Monohydrate

 

Alpha-lactose monohydrate and microcrystalline cellulose were co-spray-dried, creating a mono particulate system having two compaction mechanisms, brittle fracture and plastic deformation, within individual particles.

By combining both excipients, spray-drying was used in order to bring Lactose and Microcrystalline cellulose together. As a result a co-processed excipient was achieved that provides capability for direct compression, due to given Flowability and compactibility, making it suitable for both low dosage and high dosage formulations.

about
ADVANTAGES
  • Increased compactibility and powder flow
  • Improved Flowability and compaction properties
  • Improved content uniformity.
  • Increase tablet hardness
APPLICATIONS
  • Functional excipients used in oral solid dosage forms
  • May be used in dry granulation and capsule filling
  • Suitable for both Low dose and High dose formulations
UNIQUE FEATURES of SANCEL
  • A Hausner ratio below 1.25 or Carr’s index below 20 indicates that powders are freely flowing.
  • Excellent flow properties create the shear necessary to disperse API
  • Ideal for low-dose formulations where API content uniformity is critical.
  • Ideal tablet surface for straight forward and economical coating

Product specifications will be available soon. Please contact us for more details.

Application information will be available soon. Please contact us for more details.

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    Need more information about MCC with Lactose Monohydrate? Contact our technical team for detailed specifications and samples.