Silicified microcrystalline cellulose is a synergistic, intimate physical mixture of two components: microcrystalline cellulose and colloidal silicon dioxide. Silicified microcrystalline cellulose contains MCC up to 98% and 2% w/w colloidal silicon dioxide.
Silicification of the microcrystalline cellulose is achieved by a process, resulting in an intimate association between the colloidal silicon dioxide and microcrystalline cellulose. SMCC combines the excellent compactibility of microcrystalline cellulose with superior flow properties. Therefore, it is ideally suited to direct compression formulations where it has advantages in both flow and compactibility. It also exhibits both brittle fracture and plastic deformation characteristics, leading to superior binding properties.
- Flowability is improved
- Requires lower compression pressures
- Compactibility after wet granulation is maintained
- Compacts exhibit greater stiffness
- Higher lubrication efficiency
- Used as a filler in the formulation of capsules and tablets.
- Improved compaction properties both in wet granulation and direct compression.
- Improved blending property
UNIQUE FEATURES of SANCEL
- Loss of Compaction in Wet Granulation process is reduced.
- Beneficial in formulation of powder filled capsules
- Greater tensile strength
Unique Features of SANCEL
Angle of Repose
Customized Bulk Density
|Parameters||I.P.||U.S.P. – N.F.|
|Identification A, B||Complies||Complies|
|pH||6.0 – 8.0||6.0 – 8.0|
|Heavy Metals, ppm||NMT 10||NMT 10|
|Sulphated Ash , %||NMT 5.0||NMT 5.0|
|Loss on drying, %||NMT 8||NMT 8|
|Assay, CMC Sodium||75 – 125||75 – 125|
|Total Aerobic Microbial Count, cfu/g||NMT 100 #||NMT 100 #|
|Total Yeast And Mold Count, cfu/g||NMT 20 #||NMT 20 #|
|Pseudomonas Aeruginosa||Absent in a 10g Sample||Absent in a 10g Sample|
|Escherichia Coli||Absent in a 10g Sample||Absent in a 10g Sample|
|Staphylococcus Aureus||Absent in a 10g Sample||Absent in a 10g Sample|
|Salmonella Species||Absent in a 10g Sample||Absent in a 10g Sample|
- SMCC 90
- SMCC 90 LM
Available Packaging Type
|HDPE Bags||25 Kg|
|HDPE Bags||20 Kg|
|Paper Bags||25 Kg|
|Paper Bags||20 Kg|
*Our standard packaging is in 25 kg Bags. We can also customize packaging as per customers request at additional cost.
|20 Ft. (Approx Wt.)||10,000 Kg||12,000 Kg|
|40 Ft. (Approx Wt.)||20,000 Kg||24,000 Kg|
Other Pharmaceutical Excipients