Pharmaceutical

Microcrystalline Cellulose Spheres

SANCEL ® Microcrystalline Cellulose Spheres are Neutral Spheres for sugar free products, highly soluble & controlled released formulation products. Spheres does not contain starch or Lactose in it and are also uniform in size which makes it a perfect carrier making formulator’s life easier.

SANCEL ® MCC Spheres exhibit high mechanical strength and low friability allowing it to withstand the rigors of fluidized-bed or wurster coating process. SANCEL ® MCC Sphere is insoluble, yet it absorbs water during processing, thereby reducing particle agglomeration even at high spray rates. During dissolution it avoids film deformation or rupturing under stress. It has low chemical reactivity and hence can be freely used to layer high dose, moisture sensitive and potent actives.

about

  • Low variability of gastric emptying

  • Low dependency on nutrition state

  • Low risk of localized high drug concentrations in the GI

  • Reduced risk of sudden dose dumping

  • Lower intra- and inter-individual variability

  • High control on time and place of drug delivery

ADVANTAGES
  • Optimum water absorption.
  • High mechanical strength.
  • Very low friability level.
  • Improves stability of the finished product.
  • Higher payload permits smaller capsule sizes.
  • High abrasion resistance improves and simplifies the coating process.
APPLICATIONS
  • Used in manufacturing of granules for sustained-release applications.
  • Can also be used in taste-masking and other special applications.
  • Suitable for non-carcinogenic products.
  • Adopted for controlled-release or sustained-release formulations.
UNIQUE FEATURES of SANCEL
  • Sphericity degree average > 90%.
  • Fine and uniform particle size.
  • Agglomeration during the coating process is minimal.

Microcrystalline Cellulose Spheres - Specifications

Product Specifications

Grades of SANCEL® Microcrystalline Cellulose Spheres

Grade Mesh Micron
SANCEL® SP – 100 70 – 140 100 – 200
SANCEL® SP – 200 45 – 70 200 – 355
SANCEL® SP – 350 35 – 45 355 – 500
SANCEL® SP – 500 25 – 35 500 – 710
SANCEL® SP – 700 18 – 25 710 – 1000
SANCEL® SP – 1000 14 – 18 1000 – 1400

Packaging Details

Available Packaging Type

Type Size
HDPE Bags 25 Kg
HDPE Bags 20 Kg
Paper Bags 25 Kg
Paper Bags 20 Kg
FIBC 300 Kg

*Our standard packaging is 25 kg Bags. Custom packaging available at additional cost.

Container Packing Capacity

Container Palletized Non-Palletized
20 Ft. (Approx Wt.) 10,000 Kg 12,000 Kg
40 Ft. (Approx Wt.) 20,000 Kg 24,000 Kg

Microcrystalline Cellulose Spheres - Applications

Product Applications

Grades of SANCEL® Microcrystalline Cellulose Spheres

Grade Mesh Micron
SANCEL® SP – 100 70 – 140 100 – 200
SANCEL® SP – 200 45 – 70 200 – 355
SANCEL® SP – 350 35 – 45 355 – 500
SANCEL® SP – 500 25 – 35 500 – 710
SANCEL® SP – 700 18 – 25 710 – 1000
SANCEL® SP – 1000 14 – 18 1000 – 1400

Packaging Details

Available Packaging Type

Type Size
HDPE Bags 25 Kg
HDPE Bags 20 Kg
Paper Bags 25 Kg
Paper Bags 20 Kg
FIBC 300 Kg

*Our standard packaging is 25 kg Bags. Custom packaging available at additional cost.

Container Packing Capacity

Container Palletized Non-Palletized
20 Ft. (Approx Wt.) 10,000 Kg 12,000 Kg
40 Ft. (Approx Wt.) 20,000 Kg 24,000 Kg

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